Alan R. Davis, PhD
Department or Service
- Texas Medical Center
- Cell and gene therapy
Associate Professor, Department of Pediatrics, Section of Hematology-Oncology, Center for Cell and Gene Therapy, Baylor College of Medicine
Secondary appointment, Department of Orthopedic Surgery, Baylor College of Medicine
|Leukemia Society of America / UCLA School of Medicine||post-doctoral fellow||Department of Microbiology and Immunology||1976|
|University of California, Los Angeles||university||Doctor of Philosophy, Molecular Biology||1973|
|University of California, Los Angeles||bachelors||Bachelor of Arts, Bacteriology||1968|
Dr. Alan Davis’ research interest is in identifying signals that govern recruitment and engraftment of stem cells into bone.
Dr. Davis recently demonstrated that an early adult stem cell for the hematopoietic system also efficiently replenishes osteoblast pools in bone. The lab has also developed an adenovirus-based gene therapy system for the rapid induction of bone formation, and is currently developing this system for both spine fusions and long bone defects.
Additionally, his laboratory serves as part of the Vector Development Laboratory for the Center for Cell and Gene Therapy (CAGT) at Baylor College of Medicine. This laboratory works with investigators within Baylor College of Medicine and throughout the international research community to prepare adenoviral, retroviral, or adeno-associated viral vectors for pre-clinical research. The vector core creates more than 50 new viral vectors and provides services to over 100 different research laboratories annually.
His other interests include: osteoblast stem cell, recruitment, function, differentiation and tissue engineering.
2017 Department of Defense, Restorative Transplantation Research Program
2016 National Institutes of Health R15 grants
2015 Department of Defense, grants on heterotopic ossification
2014 Department of Defense, Panel on Respiratory Diseases
2012 Department of Defense, Laboratory featured as a success example, DOD website (CDMRP)
2010 Extremity War Injuries V, American Academy of Orthopedic Surgeons
2010 Society of Bone and Mineral Metabolism
2010 Department of Defense, Filming of our laboratory and interview for heterotopic ossification
2009 Eric Rodenberg and graduate student, Elizabeth Salisbury received Young Investigator Awards, American Society of Bone and Mineral Research
2008-2009 Abstract review committee, American Society for Cell and Gene Therapy
2007 Program Committee, American Society for Cell and Gene Therapy
2003 National Institutes of Health Study Section, NIAMS, SCOR grants
2002-2010 Department of Defense Congressionally Directed Peer Reviewed Medical Research Program
2002-2009 Human Gene Therapy
1999 HIV Vaccine Production, Safety, and Immunogenicity Testing, AIDS Pre-clinical Review Branch
1996 Human Gene Therapy, Gene Therapy
1995 Steering Committee, National Gene Vector Laboratory, National Institutes of Health