Current Research Projects

Selected Research - Multicenter Projects

Multicenter Prospective Cohort Study on Current Treatments of Legg-Calvé-Perthes Disease
Texas Children’s Hospital PI:
Rosenfeld | Partner: Texas Scottish Rite Hospital

The purpose of this study is to compare the results of different treatments for patients with LCPD disease.

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Evaluation the Necessity of Operative Irrigation and Debridement: Pediatric Randomized Trial of Type One Open Fractures (PROOF)
Texas Children’s Hospital PI:
Phillips | Partner: Ann & Robert H. Lurie Children’s Hospital of Chicago

This prospective, randomized trial will evaluate whether formal operative treatment is necessary in children with type I open fractures.

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Simple Bone Cysts In Kids (SBoCK)
Texas Children’s Hospital PI:
Shenava | Partner: Sick Kids Hospital of Toronto

This single blinded, multi-center randomized control trial compares the effectiveness of two treatment interventions for simple bone cysts: (1) curettage with puncture and (2) curettage with puncture followed by injection of tri-calcium phosphate Vitoss morsels, with the primary outcome of radiographic healing.

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The Treatment of Progressive Early Onset Spinal Deformities: A Multi-Center Outcome Study
Texas Children’s Hospital PI:
Dormans | Partner: The Growing Spine Study Group (GSSG)

This multi-center study will evaluate the long-term clinical and radiographic outcomes of Early Onset Scoliosis (EOS) and other Early Onset Spinal and Chest Wall Deformities in a large population of patients.

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Functional Studies for Skeletal Abnormalities in Rasopathies
Partner: Baylor College of Medicine Department of Molecular and Human Genetics

The purpose of this study is to create a specimen (blood, tissue, urine) repository devoted to the study of RASopathies.


Regional Variations in Pediatric Musculoskeletal Infection (CORTICES)
Texas Children’s Hospital PI: Rosenfeld | Partner: Vanderbilt University School of Medicine

The purpose of this study is to determine the regional differences in the burden, epidemiology, severity, causative pathogens and variations in clinical practice of Musculoskeletal Infection.

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Scoliosis Specific Exercises for at-risk mild AIS curves: A Multi-Site Preliminary Randomized Trial
Partner: Texas Scottish Rite Hospital

The purpose of this study is to investigate the feasibility and short-term effectiveness of scoliosis specific exercises as part of a multicenter randomized controlled trial in patients with mild AIS curves at the greatest risk of progression.


Participation Patterns in Youth Soccer
Texas Children’s Hospital PI:
McKay | Partner: University of Wisconsin-Madison

The purpose of this study is to determine the participation patterns among youth soccer athletes by geographic location.


MRI Utilization and Surgery Decision-Making in Paediatric Musculoskeletal Infections: A Prospective Multi-Center Assessment
Texas Children’s Hospital PI: Rosenfeld | Partner: University of Texas Southwestern Medical Center, Children’s Medical Center

The purpose of the study is to assess workflows for the evaluation and treatment of children with suspected or confirmed musculoskeletal infections in order to: 1) develop efficient workflows and clarify indications for MRI and surgical intervention; and 2) propose composite and component measures to the National Quality Forum of ideal processes for acquiring initial or repeat sedated MRI and performing initial or repeat surgical intervention for children with suspected or confirmed musculoskeletal infections.


Non-Operative Treatment Compared with Internal Fixation for Displaced Medial Humeral Epicondyle Fractures: A Prospective Evaluation
Texas Children’s Hospital PI: McKay | Partner: Children’s Hospital of Philadelphia

The purpose of the study is to compare non-operative and operative treatment of displaced medical humeral epicondyle fractures in children.


ACL Tear Classification Study
Texas Children’s Hospital PI: Kushare | Partner: Nationwide Children’s Hospital

The purpose of this study is to develop a classification scheme and elucidate the epidemiology of ACL (anterior cruciate ligament) tears in the pediatric population. 


Internal Projects

Our research team at Texas Children’s Hospital is actively engaged in a variety of internal research efforts with faculty investigators. Projects include retrospective, prospective, and quality improvement studies exploring the evaluation and treatment of musculoskeletal infections, perioperative management of common orthopedic conditions, and the use of the latest radiographic and imaging technology.

Over the past few years, Division research projects and manuscripts have been published and presented in a variety of locations and sources including the American Academy of Orthopaedic Surgeons Annual Meeting, the Pediatric Orthopaedic Society of North America Annual Meeting, and the Journal of Pediatric Orthopaedics.