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The Challenge

In developed countries, including the United States, Canada, and those in Western Europe, the progress made in treating childhood cancer over the last 50 years has been one of modern medicine’s true success stories.

In the United States, more than 80 percent of children survive. Worldwide, the survival is not nearly that high. An estimated 175,000 children under the age of 15 get cancer each year, and more than 100,000 of them will die because they don’t have access to adequate care.

In Sub-Saharan Africa, the childhood cancer mortality rate is estimated to be as high as 90 percent. In some countries, there’s essentially no available care for children with cancer. No diagnoses, no chemotherapy and no palliative measures.

This is due in large part to an inadequate health care infrastructure and a paucity of physicians, nurses and other health care workers trained to provide the complex care childhood cancer patients need.

At Texas Children’s, we believe our responsibility to care for children doesn’t begin and end with those who are able to come here. We have an obligation to seek out the children and future clinicians who are least likely to come to us, because that’s where we can have the greatest impact.

“Medicine is not about borders, cities or countries. Cancer doesn’t just affect children in some places and not others. As doctors who don’t just treat patients with cancer – but who care deeply for patients with cancer – it’s almost axiomatic that one must take care of children everywhere.”

— Dr. Parth Mehta, Director, Texas Children’s Global Oncology Program

In the United States and other developed nations, the dramatic improvement in prognosis results from a number of factors, including: earlier disease recognition and improved diagnosis, the development of highly effective chemotherapy, better antibiotics and supportive care, and the implementation of coordinated multi-disciplinary care among all of the necessary pediatric specialties (i.e., hematology-oncology, surgery, radiation therapy, critical care, infectious disease, nursing, and pharmacy).

Although these achievements indicate significant progress in the treatment of childhood cancer in developed nations, today 80 percent of children with cancer live in the developing world, with a large portion living in sub-Saharan Africa. In sub-Saharan Africa, approximately 100,000 children per year develop cancer and up to 90 percent of these children die.

Pediatric blood diseases in Sub-Saharan Africa occur three to four times more frequently than pediatric cancer. Disorders like sickle cell disease, which can be managed with proper medicines and care, unfortunately claim the lives of many children in these same regions. Inherited bleeding disorders, such as hemophilia, occur in newborns at the same frequency in both sub-Saharan Africa and the United States, and inherited hemoglobin disorders (e.g., sickle cell disease) are about 40 times more frequent in sub-Saharan African than in the United States whereas children born with hemophilia or sickle cell disease in the U.S. or Europe live to adulthood.

Access to quality care is often late and typically these children die without their parents or clinicians ever knowing the diagnosis. This is combined with a healthcare workforce that is not trained to treat these diseases, lack of access to modern-day medications, and a generally sub-standard healthcare infrastructure.

Videos

  • Embedded thumbnail for Texas Children's Global HOPE
    Texas Children's Global HOPE
  • Embedded thumbnail for  Creating Global HOPE: Addressing Pediatric Cancer in Africa
    Creating Global HOPE: Addressing Pediatric Cancer in Africa
  • Embedded thumbnail for Texas Children's Cancer and Hematology Centers Global Health Initiative
    Texas Children's Cancer and Hematology Centers Global Health Initiative
  • Embedded thumbnail for Texas Children's Global Health Corps Cancer Program
    Texas Children's Global Health Corps Cancer Program
  • Embedded thumbnail for Angola Sickle Cell Initiative
    Angola Sickle Cell Initiative