2019 Publications

TCH/BCM Section of Pediatric Gastroenterology, Hepatology and Nutrition Faculty and Fellows denoted in bold.


  • Gumer L, Rosen R, Gold BD, Chiou EH, Greifer M, Cohen S, Friedlander JA. Size and Prevalence of Pediatric Aerodigestive Programs in 2017. J Pediatr Gastroenterol Nutr 2019;68:e72-e76

Cystic Fibrosis

  • Cortes-Santiago N, Leung DH, Castro E, Finegold M, Wu H, Patel KR. Hepatic Steatosis Is Prevalent Following Orthotopic Liver Transplantation in Children With Cystic Fibrosis. J Pediatr Gastroenterol Nutr 2019;68:96-103
  • Freeman AJ, Sellers ZM, Mazariegos G, Kelly A, Saiman L, Mallory G, Ling SC, Narkewicz MR, Leung DH. A Multidisciplinary Approach to Pretransplant and Posttransplant Management of Cystic Fibrosis-Associated Liver Disease. Liver Transpl 2019;25:640-657
  • Goetz D, Kopp BT, Salvator A, Moore-Clingenpeel M, McCoy K, Leung DH, Kloster M, et al. Pulmonary findings in infants with cystic fibrosis during the first year of life: Results from the Baby Observational and Nutrition Study (BONUS) cohort study. Pediatr Pulmonol 2019;54:581-586.
  • Kopp BT, Joseloff E, Goetz D, Ingram B, Heltshe SL, Leung DH, Ramsey BW, et al. Urinary metabolomics reveals unique metabolic signatures in infants with cystic fibrosis. J Cyst Fibros 2019;18:507-515.
  • Lewindon PJ, Puertolas-Lopez MV, Ramm LE, Noble C, Pereira TN, Wixey JA, Hartel GF, Leung DH, Ramm GA.  Accuracy of Transient Elastography Data Combined With APRI in Detection and Staging of Liver Disease in Pediatric Patients With Cystic Fibrosis. Clin Gastroenterol Hepatol 2019;17:2561-2569 e2565
  • Ling SC, Ye W, Leung DH, Navarro OM, Weymann A, Karnsakul W, Freeman AJ, et al. Liver Ultrasound Patterns in Children With Cystic Fibrosis Correlate With Noninvasive Tests of Liver Disease. J Pediatr Gastroenterol Nutr 2019;69:351-357
  • Wu H, Vu M, Dhingra S, Ackah R, Goss JA, Rana A, Quintanilla N, Patel K, Leung DH. Obliterative Portal Venopathy Without Cirrhosis Is Prevalent in Pediatric Cystic Fibrosis Liver Disease With Portal Hypertension. Clin Gastroenterol Hepatol 2019;17:2134-2136.

Eosinophilic Gastrointestinal Disease

  • Lee J, Frey C, Miller J, Minard C, Noor M, Anagnostou A, Olive A, et al. Skin testing with different food formulations in pediatric patients with eosinophilic esophagitis. Pediatr Allergy Immunol 2019.


  • ASGE Standards Of Practice C, Qumseya B, Sultan S, Bain P, Jamil L, Jacobson B, Anandasabapathy S, Fishman DS, et al. ASGE guideline on screening and surveillance of Barrett's esophagus. Gastrointest Endosc 2019;90:335-359 e332
  • Febo-Rodriguez L, Kitagawa S, Chiou E. Colonic Diverticulitis in an Infant With Hemophagocytic Histiocytosis and Prolonged Glucocorticoid Exposure. J Pediatr Gastroenterol Nutr 2019;69:e19
  • Fishman DS, Andropoulos DB, Lightdale JR. Sedation and the Food and Drug Administration Warning: What a Pediatric Gastroenterologist, Hepatologist, and Pancreatologist Should Know. J Pediatr Gastroenterol Nutr 2019;69:3-5.
  • Higgs C, Crow YJ, Adams DM, Chang E, Hayes D, Jr., Herbig U, Huang JN, Himes RW, et al. Understanding the evolving phenotype of vascular complications in telomere biology disorders. Angiogenesis 2019;22:95-102
  • Kothari ST, Huang RJ, Shaukat A, Agrawal D, Buxbaum JL, Abbas Fehmi SM, Fishman DS, et al. ASGE review of adverse events in colonoscopy. Gastrointest Endosc 2019;90:863-876 e833.
  • Lee FC, Ramachandran V, Shah KP, Seeborg FO, Fishman DS. Esophageal Intramural Pseudodiverticulosis With Tracking in a Child With Autosomal Dominant Hyper-IgE Syndrome. J Pediatr Gastroenterol Nutr 2019;69:e19
  • Lee JK, Agrawal D, Thosani N, Al-Haddad M, Buxbaum JL, Calderwood AH, Fishman DS, et al. ASGE guideline on the role of endoscopy for bleeding from chronic radiation proctopathy. Gastrointest Endosc 2019;90:171-182 e171.
  • Lightdale JR, Liu QY, Sahn B, Troendle DM, Thomson M, Fishman DS, Endoscopy N, et al. Pediatric Endoscopy and High-risk Patients: A Clinical Report From the NASPGHAN Endoscopy Committee. J Pediatr Gastroenterol Nutr 2019;68:595-606
  • Naveed M, Jamil LH, Fujii-Lau LL, Al-Haddad M, Buxbaum JL, Fishman DS, Jue TL, et al. American Society for Gastrointestinal Endoscopy guideline on the role of endoscopy in the management of acute colonic pseudo-obstruction and colonic volvulus. Gastrointest Endosc 2019
  • Ng K, Mogul D, Hollier J, Khashab MA. Utility of functional lumen imaging probe in esophageal measurements and dilations: a single pediatric center experience. Surg Endosc 2019.
  • Queliza K, Raijman I, Fishman DS. Pancreatoscopy-Directed Electrohydraulic Lithotripsy in a Pediatric Patient with Pancreas Divisum and Cystic Fibrosis. J Pediatr Gastroenterol Nutr 2019.
  • Shah KP, Ramachandran V, Vasudevan SA, Venkatramani R, Chumpitazi BP, Fishman DS. Endoscopic Ultrasound in an Adolescent with Rectal Adenocarcinoma and Lynch Syndrome. J Pediatr Gastroenterol Nutr 2019.

Hepatology and Liver Transplantation

  • Bass LM, Shneider BL, Henn L, Goodrich NP, Magee JC, Childhood Liver Disease Research N. Clinically Evident Portal Hypertension: An Operational Research Definition for Future Investigations in the Pediatric Population. J Pediatr Gastroenterol Nutr 2019;68:763-767
  • Berauer JP, Mezina AI, Okou DT, Sabo A, Muzny DM, Gibbs RA, Hegde MR, Harpavat S, et al. Identification of Polycystic Kidney Disease 1 Like 1 Gene Variants in Children With Biliary Atresia Splenic Malformation Syndrome. Hepatology 2019;70:899-910
  • Black DD, Mack C, Kerkar N, Miloh T, Sundaram SS, Anand R, Gupta A, et al. A Prospective Trial of Withdrawal and Reinstitution of Ursodeoxycholic Acid in Pediatric Primary Sclerosing Cholangitis. Hepatol Commun 2019;3:1482-1495
  • Bonnafous P, Phan TL, Himes R, Eldin K, Gautheret-Dejean A, Prusty BK, Agut H, et al. Evaluation of liver failure in a pediatric transplant recipient of a liver allograft with inherited chromosomally integrated HHV-6B. J Med Virol 2020;92:241-250
  • Cowell E, Patel K, Heczey A, Finegold M, Venkatramani R, Wu H, Lopez-Terrada D, Miloh T. Predisposing Conditions to Pediatric Hepatocellular Carcinoma and Association With Outcomes: Single-center Experience. J Pediatr Gastroenterol Nutr 2019;68:695-699.
  • Edwards PT, Harpavat S. Commentary. Clin Chem 2019;65:1496.
  • Gorgis NM, Kennedy C, Lam F, Thompson K, Coss-Bu J, Akcan Arikan A, Nguyen T, Miloh T, et al. Clinical Consequences of Cardiomyopathy in Children With Biliary Atresia Requiring Liver Transplantation. Hepatology 2019;69:1206-1218
  • Harpavat S. MMP-7: The Next Best Serum Biomarker for Biliary Atresia? J Pediatr 2019;208:8-9
  • Kueht M, Villarreal JA, Reece E, Galvan NTN, Mysore K, Restrepo A, Quintanilla N, et al. Cutaneous Mucormycosis in Solid Organ Transplant Recipients after Hurricane Harvey: Short- and Long-term Management. Plast Reconstr Surg Glob Open 2019;7:e2041
  • Loomes KM, Spino C, Goodrich NP, Hangartner TN, Marker AE, Heubi JE, Kamath BM, Shneider BL, Hertel PM, et al. Bone Density in Children With Chronic Liver Disease Correlates With Growth and Cholestasis. Hepatology 2019;69:245-257
  • Mysore KR, Shneider BL, Harpavat S. Biliary Atresia as a Disease Starting In Utero: Implications for Treatment, Diagnosis, and Pathogenesis. J Pediatr Gastroenterol Nutr 2019;69:396-403.
  • Perito ER, Mogul DB, VanDerwerken D, Mazariegos G, Bucuvalas J, Book L, Horslen S, Miloh T, et al. The Impact of Increased Allocation Priority for Children Awaiting Liver Transplant: A Liver Simulated Allocation Model (LSAM) Analysis. J Pediatr Gastroenterol Nutr 2019;68:472-479.
  • Soler-Alfonso C, Pillai N, Cooney E, Mysore KR, Boyer S, Scaglia F. L-Cysteine supplementation prevents liver transplantation in a patient with TRMU deficiency. Mol Genet Metab Rep 2019;19:100453
  • Tam A, AlDhaheri NS, Mysore K, Tessier ME, Goss J, Fernandez LA, D'Alessandro AM, et al. Improved clinical outcome following liver transplant in patients with ethylmalonic encephalopathy. Am J Med Genet A 2019;179:1015-1019
  • Tessier MEM, Shneider BL, Brandt ML, Cerminara DN, Harpavat S. A phase 2 trial of N-Acetylcysteine in Biliary atresia after Kasai portoenterostomy. Contemp Clin Trials Commun 2019;15:100370
  • Triggs ND, Beer S, Mokha S, Hosek K, Guffey D, Minard CG, Munoz FM, RW Himes. Central line-associated bloodstream infection among children with biliary atresia listed for liver transplantation. World J Hepatol 2019;11:208-216.
  • Yoeli JK, Yoeli D, Miloh TA, Rana A, Goss JA, Munoz-Rivas F. Measles, mumps, rubella (vaccine) and varicella vaccines in pediatric liver transplant: An initial analysis of post-transplant immunity. Pediatr Transplant 2019;23:e13490

Inflammatory Bowel Disease

  • Alfaro-Cruz L, Schady D, Kellermayer R. Giant Cell [Granulomatous] Gastritis in Left-sided Paediatric Ulcerative Colitis. J Crohns Colitis 2019;13:396-397.
  • Britto S, Kellermayer R. Carbohydrate Monotony as Protection and Treatment for Inflammatory Bowel Disease. J Crohns Colitis 2019;13:942-948
  • Gettler K, Giri M, Kenigsberg E, Martin J, Chuang LS, Hsu NY, Denson LA, Kellermayer R et al. Prioritizing Crohn's disease genes by integrating association signals with gene expression implicates monocyte subsets. Genes Immun 2019;20:577-588
  • Haberman Y, Schirmer M, Dexheimer PJ, Karns R, Braun T, Kim MO, Walters TD, Kellermayer R, et al. Age-of-diagnosis dependent ileal immune intensification and reduced alpha-defensin in older versus younger pediatric Crohn Disease patients despite already established dysbiosis. Mucosal Immunol 2019;12:491-502
  • Ihekweazu FD, Fofanova TY, Queliza K, Nagy-Szakal D, Stewart CJ, Engevik MA, Hulten KG, Tatevian N, Graham  DY, Versalovic J, Petrosino JF, Kellermayer R. Bacteroides ovatus ATCC 8483 monotherapy is superior to traditional fecal transplant and multi-strain bacteriotherapy in a murine colitis model. Gut Microbes 2019;10:504-520
  • Kellermayer R. Roseburia Species: Prime Candidates for Microbial Therapeutics in Inflammatory Bowel Disease. Gastroenterology 2019;157:1164-1165
  • Krishna M, Britto S, Qian J, Ihekweazu F, Rodriguez JR, Kellermayer R. Diagnostic delay and colectomy risk in pediatric ulcerative colitis. J Pediatr Surg 2019.
  • Krishna M, Salako A, Fofanova T, Kellermayer R. Parental Education May Differentially Impact Pediatric Inflammatory Bowel Disease Phenotype Risk. Inflamm Bowel Dis 2019.
  • Krishnakumar C, Ballengee CR, Liu C, Kim MO, Baker SS, Baldassano RN, Cohen SA, Kellermayer R, et al. Variation in Care in the Management of Children With Crohn's Disease: Data From a Multicenter Inception Cohort Study. Inflamm Bowel Dis 2019;25:1208-1217.
  • Somineni HK, Venkateswaran S, Kilaru V, Marigorta UM, Mo A, Okou DT, Kellermayer R, et al. Blood-Derived DNA Methylation Signatures of Crohn's Disease and Severity of Intestinal Inflammation. Gastroenterology 2019;156:2254-2265 e2253.


Irritable Bowel Syndrome and Functional GI Disorders

  • Alfaro-Cruz L, Kaul I, Zhang Y, Shulman RJ, Chumpitazi BP. Assessment of Quality and Readability of Internet Dietary Information on Irritable Bowel Syndrome. Clin Gastroenterol Hepatol 2019;17:566-567
  • Bhatt RR, Gupta A, Labus JS, Zeltzer LK, Tsao JC, Shulman RJ, Tillisch K. Altered Brain Structure and Functional Connectivity and Its Relation to Pain Perception in Girls With Irritable Bowel Syndrome. Psychosom Med 2019;81:146-154.
  • Calarge CA, Devaraj S, Shulman RJ. Gut permeability and depressive symptom severity in unmedicated adolescents. J Affect Disord 2019;246:586-594
  • Cheng WD, Wold KJ, Bollinger LB, Ordiz MI, Shulman RJ, Maleta KM, Manary MJ, et al. Supplementation With Lactoferrin and Lysozyme Ameliorates Environmental Enteric Dysfunction: A Double-Blind, Randomized, Placebo-Controlled Trial. Am J Gastroenterol 2019;114:671-678.
  • Chumpitazi BP, Alfaro-Cruz L, Zia JK, Shulman RJ, Heitkemper MM. Commentary: Adherence with a low-FODMAP diet in irritable bowel syndrome: are eating disorders the missing link? Front Nutr 2019;6:136
  • Hollier JM, van Tilburg MAL, Liu Y, Czyzewski DI, Self MM, Weidler EM, Heitkemper M, Shulman R. Multiple psychological factors predict abdominal pain severity in children with irritable bowel syndrome. Neurogastroenterol Motil 2019;31:e13509
  • Hollister EB, Oezguen N, Chumpitazi BP, Luna RA, Weidler EM, Rubio-Gonzales M, Dahdouli M, Shulman R, et al. Leveraging Human Microbiome Features to Diagnose and Stratify Children with Irritable Bowel Syndrome. J Mol Diagn 2019;21:449-461
  • Shulman RJ, Devaraj S, Heitkemper M. Gut permeability is affected by sex and increased in children with irritable bowel syndrome but not in functional abdominal pain. Neurogastroenterol Motil 2019:e13765.
  • Shulman RJ, Ohman L, Stridsberg M, Cain K, Simren M, Heitkemper M. Evidence of increased fecal granins in children with irritable bowel syndrome and correlates with symptoms. Neurogastroenterol Motil 2019;31:e13486.


  • Davidovics ZH, Michail S, Nicholson MR, Kociolek LK, Pai N, Hansen R, Schwerd T, Kellermayer R, et al. Fecal Microbiota Transplantation for Recurrent Clostridium difficile Infection and Other Conditions in Children: A Joint Position Paper From the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition and the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition. J Pediatr Gastroenterol Nutr 2019;68:130-143.
  • Engevik MA, Luk B, Chang-Graham AL, Hall A, Herrmann B, Ruan W, Endres BT, et al. Bifidobacterium dentium Fortifies the Intestinal Mucus Layer via Autophagy and Calcium Signaling Pathways. mBio 2019;10.
  • Ford SL, Lohmann P, Preidis GA, Gordon PS, O'Donnell A, Hagan J, Venkatachalam A, et al. Improved feeding tolerance and growth are linked to increased gut microbial community diversity in very-low-birth-weight infants fed mother's own milk compared with donor breast milk. Am J Clin Nutr 2019;109:1088-1097
  • Kellermayer R. Fecal microbiota transplantation: great potential with many challenges. Transl Gastroenterol Hepatol 2019;4:40
  • Kellermayer R, Kahn SA. The Gut Microbiome: A Difficult Target for Translational Studies of Clostridium difficile Colonization. J Pediatr Gastroenterol Nutr 2019;68:463-464.
  • Kociolek LK, Davidovics ZH, Kahn SA, Kellermayer R. Response to: Treatment of (Recurrent) Clostridioides difficile Infections in Children and Adults. J Pediatr Gastroenterol Nutr 2019;69:e58-e59.
  • Nicholson MR, Mitchell PD, Alexander E, Ballal S, Bartlett M, Becker P, Davidovics Z, Queliza K, Kellermayer R, et al. Efficacy of Fecal Microbiota Transplantation for Clostridium difficile Infection in Children. Clin Gastroenterol Hepatol 2019
  • Shin A, Preidis GA, Shulman R, Kashyap PC. The Gut Microbiome in Adult and Pediatric Functional Gastrointestinal Disorders. Clin Gastroenterol Hepatol 2019;17:256-274
  • Spinner JA, Bocchini CE, Luna RA, Thapa S, Balderas MA, Denfield SW, Dreyer WJ, Nagy-Szakal D, Ihekweazu FD, Versalovic J, Savidge T, Kellermayer R. Fecal microbiota transplantation in a toddler after heart transplant was a safe and effective treatment for recurrent Clostridiodes difficile infection: A case report. Pediatr Transplant 2019:e13598.

Neurogastroenterology and Motility

  • Abell TL, Yamada G, McCallum RW, Van Natta ML, Tonascia J, Parkman HP, Koch KL, Shulman R, et al. Effectiveness of gastric electrical stimulation in gastroparesis: Results from a large prospectively collected database of national gastroparesis registries. Neurogastroenterol Motil 2019;31:e13714
  • Febo-Rodriguez L, Chumpitazi BP, Shulman RJ. Childhood gastroparesis is a unique entity in need of further investigation. Neurogastroenterol Motil 2019:e13699
  • Grover M, Dasari S, Bernard CE, Chikkamenahalli LL, Yates KP, Pasricha PJ, Sarosiek I, Shulman R, et al. Proteomics in gastroparesis: unique and overlapping protein signatures in diabetic and idiopathic gastroparesis. Am J Physiol Gastrointest Liver Physiol 2019;317:G716-G726
  • Khashab MA, Vela MF, Thosani N, Agrawal D, Buxbaum JL, Abbas Fehmi SM, Fishman DS, et al. ASGE guideline on the management of achalasia. Gastrointest Endosc 2019.
  • McOmber M, Rafati D, Cain K, Devaraj S, Weidler EM, Heitkemper M, Shulman RJ. Increased Gut Permeability in First-degree Relatives of Children with Irritable Bowel Syndrome or Functional Abdominal Pain. Clin Gastroenterol Hepatol 2019
  • Rosenfeld EH, Chumpitazi BP, Castro E, Naik-Mathuria B. Diffuse Intestinal Ganglioneuromatosis Causing Severe Intestinal Dysmotility in a Child With a PTEN Mutation. J Pediatr Gastroenterol Nutr 2019;68:e35-e37
  • Soni KG, Halder T, Conner ME, Preidis GA. Sexual dimorphism in upper gastrointestinal motility is dependent on duration of fast, time of day, age, and strain of mice. Neurogastroenterol Motil 2019;31:e13654
  • Yu YR, Rosenfeld EH, Chiou EH, Chumpitazi BP, Fallon SC, Brandt ML. High-resolution manometric guidance during laparoscopic Heller myotomy: Impact on quality of life and symptom severity for children with achalasia. J Pediatr Surg 2019;54:1063-1068.


  • Cruz LA, Barton K, Hertel P, Carter BA, Bergner EM, Garcia-Prats JA, Mehollin-Ray AR, et al. "TPN-oma": A Rare Complication of Lipid Extravasation with UVC Misplacement. J Pediatr Gastroenterol Nutr 2019
  • Reiter-Purtill J, Ley S, Kidwell KM, Mikhail C, Austin H, Chaves E, Rofey DL, et al. Change, predictors and correlates of weight- and health-related quality of life in adolescents 2-years following bariatric surgery. Int J Obes (Lond) 2019


  • Bellin MD, Lowe M, Zimmerman MB, Wilschanski M, Werlin S, Troendle DM, Shah U, Fishman DS, et al. Diabetes Mellitus in Children with Acute Recurrent and Chronic Pancreatitis: Data From the INternational Study Group of Pediatric Pancreatitis: In Search for a CuRE Cohort. J Pediatr Gastroenterol Nutr 2019;69:599-606.
  • Committee ASoP, Buxbaum JL, Abbas Fehmi SM, Sultan S, Fishman DS, Qumseya BJ, Cortessis VK, et al. ASGE guideline on the role of endoscopy in the evaluation and management of choledocholithiasis. Gastrointest Endosc 2019;89:1075-1105 e1015.
  • Lin TK, Abu-El-Haija M, Nathan JD, Palermo JP, Barth B, Bellin M, Fishman DS, et al. Pancreas Divisum in Pediatric Acute Recurrent and Chronic Pancreatitis: Report From INSPPIRE. J Clin Gastroenterol 2019;53:e232-e238.
  • Lin TK, Fishman DS, Giefer MJ, Liu QY, Troendle D, Werlin S, Lowe ME, et al. Functional Pancreatic Sphincter Dysfunction in Children: Recommendations for Diagnosis and Management. J Pediatr Gastroenterol Nutr 2019;69:704-709.
  • Liu QY, Abu-El-Haija M, Husain SZ, Barth B, Bellin M, Fishman DS, Freedman SD, et al. Risk Factors for Rapid Progression From Acute Recurrent to Chronic Pancreatitis in Children: Report From INSPPIRE. J Pediatr Gastroenterol Nutr 2019;69:206-211.
  • Motil KJ, Lane JB, Barrish JO, Annese F, Geerts S, McNair L, Skinner SA, et al. Biliary Tract Disease in Girls and Young Women With Rett Syndrome. J Pediatr Gastroenterol Nutr 2019;68:799-805
  • Palermo TM, Murray C, Aalfs H, Abu-El-Haija M, Barth B, Bellin MD, Ellery K, Fishman DS et al. Web-based cognitive-behavioral intervention for pain in pediatric acute recurrent and chronic pancreatitis: Protocol of a multicenter randomized controlled trial from the study of chronic pancreatitis, diabetes and pancreatic cancer (CPDPC). Contemp Clin Trials 2019;88:105898
  • Schwarzenberg SJ, Uc A, Zimmerman B, Wilschanski M, Wilcox CM, Whitcomb DC, Werlin SL, Fishman DS, et al. Chronic Pancreatitis: Pediatric and Adult Cohorts Show Similarities in Disease Progress Despite Different Risk Factors. J Pediatr Gastroenterol Nutr 2019;68:566-573