Conditions We Treat

About Bone Tumors

Bone tumors account for approximately 6% of malignancies in the pediatric population. The most common forms of bone tumors that arise in the bone are osteosarcoma and Ewing sarcoma. Osteosarcoma arises from bone cells and is more common in older teenagers, whereas Ewing sarcoma arises from neural crest cells and tends to occur in younger children. Ewing sarcoma belongs to a larger family known as the Ewing Sarcoma Family of Tumors (ESFT) that can arise in other tissues of the body as well as in the bone. In almost all cases, the cause of these tumors is not known, but there is much research being conducted to try to understand factors that initiate these tumors and allow them to progress in order to find better treatments. Both tumors are curable and are treated by a combination of chemotherapy, surgery +/- radiation therapy. This requires an integrated team of caregivers that includes pediatric oncology, general surgery, orthopedic surgery and radiation oncology. The most common malignant bone tumors in children and adolescents are osteosarcoma and Ewing sarcoma. Patients with these tumors require multidisciplinary care from a team of providers that includes pediatric oncology, orthopedic oncologic surgery, physical therapy, pathologists and radiologists with expertise in bone diseases, specialized nursing care, as well as pediatric social workers and child life specialists. The Bone Tumors Program provides all of these services to our patients. Patients with bone lesions, whether suspected or known to be malignant, will receive initial evaluation in our Musculoskeletal Tumor Clinic by both a pediatric oncologist and orthopedic surgeon. Patients with benign bone tumors will receive follow up care in close follow-up with the Orthopedic Service at Texas Children’s Hospital. Patients with malignant bone tumors will receive care from the Bone Tumor Program at Texas Children’s Cancer Center, the hematology-oncology treatment center of Texas Children’s Hospital.