The Biennial William T. Shearer "Innovations in Primary Immunodeficiency and Clinical Immunology" Symposium

February 11, 2017 at 7AM
JW Marriott Houston Downtown
806 Main St, Houston, TX 77002

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About the Conference

The goal of the symposium is to increase awareness among the medical community of the importance of early detection of PIDD and assist in accurate diagnosis as there are more than 300 identified PIDD genes to date.  It has been reported in published clinical retrospective studies that delayed diagnosis of PIDD results in increased morbidity and mortality.  Furthermore, it has also been shown that there is a significant delay in the diagnosis of PIDD among physicians in the at-large community in comparison to the expert community.  With the large number of genes that can contribute to PIDDs and also how similar genes can cause different clinical presentations in patients, it’s important to continually update the community on how to properly identify and diagnose patients.

Through presentations and discussions among physicians, scientists, and nurses on the utilization of new diagnostics tools for the early detection of PIDD, the vast improvement in patient outcome through early detection, and understanding emerging immunological barriers to the successful treatment of PIDD, is critically imperative to ameliorate avoidable morbidity and mortality among patients with PIDD.

The program will:

  1. Provide updates for the treatment of Primary Immunodeficiency Diseases (PIDD)
  2. Provide education on innovative diagnostic tests for the early and accurate detection of Primary Immunodeficiency Diseases (PIDD)
  3. Provide update on newly described PIDD genes, namely within the past two years since the previous 2015 William T. Shearer Innovations in Primary Immunodeficiency and Clinical Immunology Symposium
  4. Describe updates in the field of Autoinflammatory and Lymphoproliferative Disease
  5. Provide insights into emerging immunological barriers faced by patients with PIDD
  6. Update on new and innovative therapies for Food Allergies


  • Advancement in Clinical Immunology – Jordan Orange, MD, PhD, Section Chief, Immunology, Allergy & Rheumatology, Texas Children’s Hospital, Houston, TX
  • Keynote Address: New innovations and discoveries in Primary Immune deficiency diseases - Bodo Grimbacher, MD, PhD, University of Freiburg, Germany
  • Center for Mendelian Genomics Project and the new discoveries from the Houston Project Collaboration, James R. Lupski, MD PhD, DSc (hon), FAAP,FACMG, FAAAS, FAAS,Baylor College of Medicine, Houston, TX
  • Multidisciplinary Approach Diagnostic Evaluation and Research in Primary Immune deficiencies diseases – Chivon McMullen-Jackson, RN, Texas Children’s Hospital, Houston, TX
  • The Innovations in Diagnosis and Treatment of Primary Immune Deficiency Diseases in Latin America- Francisco Espinosa, MD, National Institute of Pediatrics, Mexico City, Mexico
  • Results and Discoveries from the Houston Project- The Collaboration in Ecuador- Luis Alberto (Mateo) Pedroza, PhD, University of San Francisco, Quito, Ecuador
  • Therapeutic Uses of IVIG - Ricardo Sorensen, MD, LSU Health Sciences Center, New Orleans, LA
  • Innovations and Advancement in the Texas Children’s Hospital Food Allergy Center- Sara Anvari, MD Texas Children’s Hospital, Baylor College of Medicine, Houston, Texas
  • Innovations in the Discovery and Treatment of Lymphoproliferative Disorders- Carl Allen, MD, Texas Children’s Hospital, Houston, Texas
  • New Discoveries in Gene Therapy and Innovations in Treatment of Primary Immune Deficiency Disease- Sung-Yun Pai, MD, Boston’s Children’s Hospital/Dana-Farber Cancer Institute, Boston, Massachusetts
  • New Innovations in Autoimmune and Auto-inflammatory Diseases- Virginia Pascual, MD, Baylor Institute for Immunology Research, Dallas, Texas  
  • Innate Regulation of Natural Killer Cell Responses to Influenza A infections- Silke Paust, PhD, Baylor College of Medicine
  • Immune Regulation in Space Travel- Brian Crucian, PhD, NASA, Houston, TX

Early Registration Deadline

Friday, January 20, 2017


Early registration - until January 20, 2017: $25
Late registration and onsite registration: $40

Location and Hotel Accommodations

JW Marriott Houston Downtown
806 Main St, Houston, TX 77002


Complimentary Valet Parking is included with Registration

CME/CNE Details and Accreditation

Texas Children's Hospital is accredited by the Texas Medical Association to provide continuing medical education for physicians.

Texas Children's Hospital is an approved provider of continuing nursing education by the Texas Nurses Association - Approver, an accredited approver by the American Nurses Credentialing Center’s Commission on Accreditation.

Contact information

For questions or more information, please email Ruth Herrera at, (832) 824-2030