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The Center for Vaccine Awareness and Research

Vaccine
research

The Center for Vaccine Awareness and Research specialists are involved in several active research projects and have participated in numerous vaccine research studies that have helped shape the immunization landscape.

Current research studies/projects include:


Safety and Immunogenicity of Tdap Vaccine in Healthy Pregnant Women, Safety in Their Neonates, and Effect of Maternal Immunization on Infant Immune Responses to DTaP Vaccine

 
Sponsored by the National Institute of Allergy & Infectious Diseases
 
Investigators:
Carol J. Baker, M.D., Flor Munoz, M.D., and C. Mary Healy, M.D.

Description:
This phase I study aims to evaluate the newly licensed Tdap vaccine (Tetanus toxoid-diphtheria toxoid-acellular pertussis) in healthy pregnant women vaccinated during 30 to 32 weeks of gestation for their newborn infants. 

This study will also assess the immune response of pregnant women to Tdap vaccine, define the efficiency with which maternal antibodies are transferred across the placenta to the newborn infant and evaluate if high maternal antibody levels have an effect on the infant’s immune response to DTaP (Diphtheria toxoid-Tetanus toxoid-acellular Pertussis) vaccine given as part of the routine 2, 4 and 6 month infant immunization series. This study will provide important information regarding the safety and feasibility of using maternal immunization as a strategy to prevent pertussis infection in mothers and severe, life-threatening pertussis in their very young infants who are too young to have completed their own 3-dose primary immunization series.
 


CDC/SAM Immunization Small Grants Program, 2005 Innovation in Improving Immunization Delivery to Children and/or Adolescents

Investigating Barriers to Accessing Information Regarding Private Medical Insurance Coverage for Adolescent Vaccinations

Sponsored by the Society for Adolescent Medicine and the Centers for Disease Control and Prevention

Investigators:
Julie Boom, M.D., and Amy Middleman, M.D., M.P.H., M.S.E.D.

An often-cited barrier in the effective immunization of adolescents is the financial burden of vaccination. With new immunization recommendations and new vaccines specifically for adolescents, we sought to uncover underlying financial factors that could affect the uptake of new vaccine recommendations for adolescents. Through informal phone calls to private insurance companies in Texas, however, we encountered barriers to accessing a knowledgeable representative capable of releasing information regarding vaccination plan options and reimbursements. We therefore determined that our study actually required a more fundamental component of the investigation, including the primary obstacles to accessing information regarding insurance coverage for newly recommended adolescent vaccines.

Based on this premises, our proposal aims to investigate the primary factors that impede accessing information regarding insurance coverage for newly recommended adolescent vaccines. The specific objectives include:

  1. Gathering data regarding the barriers to accessing health insurance coverage information for new ACIP adolescent vaccination recommendations.

  2. Investigating the association of these barriers with characteristics of private insurance companies, including size and type of company and the type and number of health plans each company offers employers.

  3. Analyzing any available information regarding benefits and physician reimbursement for adolescent vaccination.

Through telephone surveys, we assess the barriers to accessing reimbursement information from private insurance companies in Texas, New York, and Oregon. The stepwise survey includes 3 main themes/tiers representing pervasive situations we encountered when requesting information from private health insurance companies. These 3 major themes include: (1) access to key informants (including reaching a human contact); (2) availability of reimbursement information (willingness to respond to surveys, and identifying the key person with reimbursement information); and (3) attainment of adolescent vaccine reimbursement information (actual reimbursement data).

After gathering data regarding these barriers, we will investigate the association of these barriers with characteristics of private insurance companies and analyze any available information regarding benefits and physician reimbursement for adolescent vaccination. Results from this study will influence future research plans to investigate these barriers nationally and determine the impact of physician reimbursement on adolescent immunization coverage and healthcare utilization.
 

 

 
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