Department or Service
Department of Surgery, General Surgery
Specialty
General Surgery
Primary Location
Texas Children's Hospital
Contact Information
6701 Fannin
Suite 1210
Houston, TX 77030
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Phone: 832-822-3135
Fax: 832-825-3141
Sanjeev A. Vasudevan, M.D.
Attending Surgeon, Pediatric Surgery Service - Texas Children's Hospital
Assistant Professor of Surgery, Baylor College of Medicine
Medical School
Emory University School of Medicine, Doctor of Medicine, 2001
Residency
Baylor College of Medicine, General Surgery, 2009
Fellowship
Baylor College of Medicine, Pediatric Surgery, 2011
From Dr. Vasudevan
Dr. Vasudevan is a pediatric surgeon who specializes in pediatric surgical oncology. In addition to performing general neonatal and pediatric surgery, he is a member of the Surgical Oncology Team at Texas Children’s Hospital and is actively involved with taking care of patients with neuroblastoma, liver cancer, renal tumors, and sarcomas. His research program consists of clinical and molecular biology research focusing on pediatric solid tumors, in particular neuroblastoma and liver cancer. He is a member of the Carl C. Anderson, Sr. and Marie Jo Anderson Charitable Foundation Laboratory for Neuroblastoma Research as well as the Texas Children’s Liver Tumor Center.
Dr. Vasudevan’s research laboratory focuses on validation of potential therapeutic targets found in neuroblastoma and hepatoblastoma. During his postdoctoral training in the Texas Children’s Cancer Center, Dr. Vasudevan cloned two novel genes, NDSP and DUSP26, which were found to be specifically overexpressed in neuroblastoma and play critical roles in tumor growth and chemosensitivity. He is furthering this work as a principal investigator by focusing on the function and regulation of kinases and phosphatases in pediatric malignancy by defining their roles as novel tumor suppressors or oncogenes. Dr. Vasudevan’s lab hopes to validate multiple targets in order to find novel and less toxic therapeutic agents to improve outcomes for children with solid tumors.
Dr. Vasudevan is certified by the American Board of Surgery in General Surgery and in Pediatric Surgery.
Professional Organizations *
- Phi Beta Kappa
Member - American Association for Cancer Research
Associate Member - American College of Surgeons
Resident and Associate Society Member
Selected Publications
Vasudevan SA, Shang X, Yu Y, Ge N, Ludwig AD, Wesson CL, Wang K, Burlingame SM, Zhao YJ, Rao PH, Lu X, Russell HV, Okcu MF, Hicks MJ, Shohet JM, Donehower LA, Nuchtern JG, Yang J. Dual-specificity phosphatase 26 is a novel p53 phosphatase and inhibits p53 tumor suppressor functions in human neuroblastoma.Oncogene 2010 Sep 2;29(35):4938-46.
Vasudevan SA, Shang X, Chang S, Ge N, Diaz-Miron JL, Russell HV, Hicks MJ, Ludwig AD, Wesson CL, Burlingame SM, Kim ES, Khan J, Yang J, Nuchtern JG. Neuroblastoma-derived secretory protein is a novel secreted factor overexpressed in neuroblastoma.Molecular Cancer Therapeutics 2009 Aug;8(8):2478-89. Epub 2009 Aug 11. Erratum in: Mol Cancer Ther. 2009 Sep;8(9):2771.
Hassan SF, Mathur S, Magliaro TJ, Larimer EL, Ferrell LB, Vasudevan SA, Patterson DM, Louis CU, Russell HV, Nuchtern JG, Kim ES. Needle core vs open biopsy for diagnosis of intermediate- and high-risk neuroblastoma in children. Journal of Pediatric Surgery 2012 Jun;47(6):1261-6. Review. PMID: 22703803.
Mathur S, Vasudevan SA, Patterson DM, Hassan SF, Kim ES. Novel use of glycopyrrolate (Robinul) in the treatment of anastomotic leak after repair of esophageal atresia and tracheoesophageal fistula. Journal of Pediatric Surgery 2011 Mar;46(3):e29-32. PMID: 21376184.
Shang X, Vasudevan SA, Yu Y, Ge N, Ludwig AD, Wesson CL, Wang K, Burlingame SM, Zhao YJ, Rao PH, Lu X, Russell HV, Okcu MF, Hicks MJ, Shohet JM, Donehower LA, Nuchtern JG, Yang J. Dual-specificity phosphatase 26 is a novel p53 phosphatase and inhibits p53 tumor suppressor functions in human neuroblastoma. Oncogene 2010 Sep 2;29(35):4938-46. PMID: 20562916.
* Texas Children's Hospital physicians' licenses and credentials are reviewed prior to practicing at any of our facilities. Sections titled From the Doctor, Professional Organizations and Publications were provided by the physician's office and were not verified by Texas Children's Hospital.
