Credentials for
Saul J. Karpen, M.D., Ph.D.

Name: Saul J. Karpen, M.D., Ph.D.

Texas Children's Position: Director, Texas Children's Liver Center; Medical Director, Texas Children's Liver Transplantation Program; and Chief of Service, Texas Children's Biliary Atresia Clinic

Other Positions: Faculty, Translational Biology and Molecular Medicine Executive Committee, Baylor College of Medicine

Specialty(ies):

Gastroenterology (stomach, digestion)

Liver

Primary Focus: Biliary Atresia; Liver Diseases in Infants and Children; New treatments of Liver Disease; Viral Hepatitis; and Clinical and Basic Research in Liver Disease; NIH-Funded Research on Biliary Atresia

Publications:
Author	The Texas Children's Liver Center Transplant Handbook
Invited Review	Karpen SJ. Update on the etiologies and management of neonatal cholestasis. Clin Perinatol 29:159-180, 2002.
Author	Ghose R, TL Zimmerman, S Thevananther, SJ Karpen. Endotoxin leads to rapid nuclear export of hepatic RXRa. Nucl Recept, 2:4, Aug. 2, 2004.
Author	Balistreri WF, Bezerra JA, Jansen P, Karpen SJ, Shneider BL and Suchy FJ. Intrahepatic Cholestasis: Summary of an American Association for the Study of Liver Diseases Single-Topic Conference. 19.3. Hepatology 42 (1):222-235, 2005.
Author	Balistreri WF, Bezerra JA, Jansen P, Karpen SJ, Shneider BL and Suchy FJ. Intrahepatic Cholestasis: Summary of an AASLD Single-Topic Conference. 19.3. Hepatology 42 (1):222-235, 2005.
Author	Karpen SJ. Exercising the Nuclear Option to Treat Cholestasis. Commentary on article Wagner, M. et al. CAR and PXR agonists stimulate hepatic bile acid and bilirubin detoxification and elimination pathways in mice. Hepatology 42 (2):267-2697, 2005.
Invited Review	Karpen, SJ. Nuclear receptor regulation of hepatic function. J Hepatology 36:832-50, 2002.
Author	Barshes NR, Lee TC, Balkrishnan R, Karpen SJ, Carter BA, Goss JA. Orthotopic liver transplantation for biliary atresia: The U.S. experience. Liver Transpl. 2005 Oct;11:1193-2000.
Author	Horst, D. and S.J. Karpen. Bile formation and cholestasis. In: R.A. Polin, W.W. Fox, and S.H. Abman, eds. Fetal and Neonatal Physiology, 3rd Edition. Philadelphia: Saunders, 2003, pp. 1186-1198.
Author	Karpen, S.J. Transcriptional regulation of hepatobiliary transporters. In: M. Trauner and P. Jansen, eds. Molecular Pathogenesis of Cholestasis. Georgetown, TX: Eurekah.com/Landes Bioscience and Kluwer Academic/Plenum Publishers, 2004, pp. 96-111.
Author	Kurbegov, A. and Karpen, S.J. Bile formation and cholestasis. In: W.A Walker, O.L. Goulet, R.E. Kleinman, I.R. Sanderson, P.M. Sherman, B.L. Shneider, eds. Pediatric Gastrointestinal Disease, 4th Edition. Ontario: BC Decker, Inc., 2004, pp. 70-79.
Associate Editor	Hepatology

Professional Organizations:
Chair	NASPGHAN Hepatology Committee
Member	North American Society for Pediatric Gastroenterology and Nutrition
Member	American Gastroenterological Association
Chair	AASLD Basic Research Committee

Contact Information:

6701 Fannin St, Clinical Care Center

Houston TX 77030.

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Phone: 832-824-3754