In this issue

Director's Corner by David G. Poplack, M.D.

Gastrointestinal stromal tumors (GIST)
by Alberto Pappo, M.D.

Turning the Immune System Against Neuroblastoma
by Doug Myers, M.D. and Malcolm Brenner, M.D., Ph.D.

Pediatric Hematology Oncology Subspecialty
Training in the United States
by Lindsay B. Kilburn, M.D. and C. Philip Steuber, M.D.

Regulatory and Ethical Issues in the Treatment of Children
by Bambi Grilley, R.Ph., C.C.R.P., C.C.R.C., C.I.P., Stacey Berg, M.D.
and Cynthia Boudreaux, M.Ed., C.C.R.P.

Dr. David Poplack

Director's Corner

Welcome to the fourth issue of Perspectives on Childhood Cancer, the international eJournal of Texas Children’s Cancer Center. This issue contains articles by experts at Texas Children’s Cancer Center pertaining to a variety of subjects: gastrointestinal stromal tumors, neuroblastoma, subspecialty training in the United States, and regulatory and ethical issues in the treatment of children.

Texas Children’s Cancer Center is one of the largest pediatric cancer programs in the United States. We offer innovative therapies for all forms of childhood cancer, and we are dedicated to improving the outcome of all patients afflicted with these diseases. Texas Children's Cancer Center is committed to a future free from the threat of childhood cancer.

We hope you enjoy reading Perspectives on Childhood Cancer and that you will share it with your colleagues. Please feel free to
e-mail us with questions and topic ideas.

Sincerely,
David G. Poplack, M.D.
Director, Texas Children's Cancer Center
Co-Editor, Principles and Practices of Pediatric Oncology